Enhanced internalization of ErbB2 in SK-BR-3 cells with multivalent forms of an artificial ligand

Targeting and down-regulation of ErbB2, a member of EGF receptor family, is regarded as one of the key aspect for cancer treatment because it is often overexpressed in breast and ovarian cancer cells. Although natural ligands for ErbB2 have not been found, unlike other ErbB receptors, EC-1, a 20-ami...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vaidyanath, Arun, Hashizume, Toshihiro, Nagaoka, Tadahiro, Takeyasu, Nao, Satoh, Hitomi, Chen, Ling, Wang, Jiyou, Kasai, Tomonari, Kudoh, Takayuki, Satoh, Ayano, Fu, Li, Seno, Masaharu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Publishing Ltd 2011
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822962/
https://ncbi.nlm.nih.gov/pubmed/21323863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01277.x
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