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bcl-2-specific siRNAs restore Gemcitabine sensitivity in human pancreatic cancer cells
Gemcitabine has been shown to ameliorate disease related symptoms and to prolong overall survival in pancreatic cancer.Yet, resistance to Gemcitabine is commonly observed in this tumour entity and has been linked to increased expression of anti-apoptotic bcl-2. We therefore investigated if and to wh...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3822833/ https://ncbi.nlm.nih.gov/pubmed/17378914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2007.00013.x |
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