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Variants of bcl-2 specific siRNA for silencing antiapoptotic bcl-2 in pancreatic cancer

Background and aims: Pancreatic cancer remains a devastating diagnosis with only limited therapeutic options. Specific inhibition of expression of target genes has become possible using small interfering (si) RNAs. We therefore investigated how far siRNA specific for bcl-2 may serve as a therapeutic...

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Detalhes bibliográficos
Main Authors: Ocker, M, Neureiter, D, Lueders, M, Zopf, S, Ganslmayer, M, Hahn, E G, Herold, C, Schuppan, D
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by Gut 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774673/
https://ncbi.nlm.nih.gov/pubmed/16099798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.056192
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