Variants of bcl-2 specific siRNA for silencing antiapoptotic bcl-2 in pancreatic cancer

Background and aims: Pancreatic cancer remains a devastating diagnosis with only limited therapeutic options. Specific inhibition of expression of target genes has become possible using small interfering (si) RNAs. We therefore investigated how far siRNA specific for bcl-2 may serve as a therapeutic...

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Main Authors: Ocker, M, Neureiter, D, Lueders, M, Zopf, S, Ganslmayer, M, Hahn, E G, Herold, C, Schuppan, D
Format: Artigo
Sprog:Inglês
Udgivet: Copyright 2005 by Gut 2005
Fag:
Pancreatic Cancer
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774673/
https://ncbi.nlm.nih.gov/pubmed/16099798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.056192
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