Persistent cAMP Signaling by TSH Receptors Revealed by Phosphodiesterase Inhibition

BACKGROUND: It is controversial whether persistent signaling by the thyrotropin (TSH) receptor (TSHR) is cell-type specific. We reported persistent TSHR signaling in human embryonic kidney 293 (HEK293) cells expressing human TSHRs (HEK-TSHRs), whereas another group reported persistent signaling in m...

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Detalhes bibliográficos
Main Authors: Geras-Raaka, Elizabeth, Neumann, Susanne, Gershengorn, Marvin C.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822400/
https://ncbi.nlm.nih.gov/pubmed/23713896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2013.0089
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