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Targeting folded RNA: A branched peptide boronic acid that binds to a large surface area of HIV-1 RRE RNA()
On-bead high throughput screening of a medium sized (1000–2000 Da) branched peptide boronic acid (BPBA) library consisting of 46,656 unique sequences against HIV-1 RRE RNA generated peptides with binding affinities in the low micromolar range. In particular, BPBA1 had a K(d) of 1.4 µM with RRE IIB,...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3821739/ https://ncbi.nlm.nih.gov/pubmed/23925474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ob41053f |
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