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Structural and thermodynamic insight into phenylalanine hydroxylase from the human pathogen Legionella pneumophila()
Phenylalanine hydroxylase from Legionella pneumophila (lpPAH) has a major functional role in the synthesis of the pigment pyomelanin, which is a potential virulence factor. We present here the crystal structure of lpPAH, which is a dimeric enzyme that shows high thermostability, with a midpoint dena...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3821034/ https://ncbi.nlm.nih.gov/pubmed/24251098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2013.08.006 |
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