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Phenylalanine Hydroxylase from Legionella pneumophila Is a Thermostable Enzyme with a Major Functional Role in Pyomelanin Synthesis

BACKGROUND: Legionella pneumophila is a pathogenic bacterium that can cause Legionnaires’ disease and other non-pneumonic infections in humans. This bacterium produces a pyomelanin pigment, a potential virulence factor with ferric reductase activity. In this work, we have investigated the role of ph...

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Detalhes bibliográficos
Main Authors: Flydal, Marte I., Chatfield, Christa H., Zheng, Huaixin, Gunderson, Felizza F., Aubi, Oscar, Cianciotto, Nicholas P., Martinez, Aurora
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458870/
https://ncbi.nlm.nih.gov/pubmed/23049981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046209
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