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Secreted Pyomelanin of Legionella pneumophila Promotes Bacterial Iron Uptake and Growth under Iron-Limiting Conditions

Iron acquisition is critical to the growth and virulence of Legionella pneumophila. Previously, we found that L. pneumophila uses both a ferrisiderophore pathway and ferrous iron transport to obtain iron. We now report that two molecules secreted by L. pneumophila, homogentisic acid (HGA) and its po...

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Detalles Bibliográficos
Main Authors: Zheng, Huaixin, Chatfield, Christa H., Liles, Mark R., Cianciotto, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811826/
https://ncbi.nlm.nih.gov/pubmed/23980114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00858-13
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