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Epidermal Growth Factor Receptor (EGFR) Signaling Regulates Epiphyseal Cartilage Development through β-Catenin-dependent and -independent Pathways

The epidermal growth factor receptor (EGFR) is an essential player in the development of multiple organs during embryonic and postnatal stages. To understand its role in epiphyseal cartilage development, we generated transgenic mice with conditionally inactivated EGFR in chondrocytes. Postnatally, t...

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Detalhes bibliográficos
Main Authors: Zhang, Xianrong, Zhu, Ji, Li, Yumei, Lin, Tiao, Siclari, Valerie A., Chandra, Abhishek, Candela, Elena M., Koyama, Eiki, Enomoto-Iwamoto, Motomi, Qin, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820861/
https://ncbi.nlm.nih.gov/pubmed/24047892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.463554
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