Reduced EGFR signaling enhances cartilage destruction in a mouse osteoarthritis model

Osteoarthritis (OA) is a degenerative joint disease and a major cause of pain and disability in older adults. We have previously identified epidermal growth factor receptor (EGFR) signaling as an important regulator of cartilage matrix degradation during epiphyseal cartilage development. To study it...

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Detalhes bibliográficos
Publicado no:Bone Res
Main Authors: Zhang, Xianrong, Zhu, Ji, Liu, Fei, Li, Yumei, Chandra, Abhishek, Levin, L Scott, Beier, Frank, Enomoto-Iwamoto, Motomi, Qin, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472123/
https://ncbi.nlm.nih.gov/pubmed/26120493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2014.15
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