Reduced EGFR signaling enhances cartilage destruction in a mouse osteoarthritis model

Osteoarthritis (OA) is a degenerative joint disease and a major cause of pain and disability in older adults. We have previously identified epidermal growth factor receptor (EGFR) signaling as an important regulator of cartilage matrix degradation during epiphyseal cartilage development. To study it...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Bone Res
Päätekijät: Zhang, Xianrong, Zhu, Ji, Liu, Fei, Li, Yumei, Chandra, Abhishek, Levin, L Scott, Beier, Frank, Enomoto-Iwamoto, Motomi, Qin, Ling
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472123/
https://ncbi.nlm.nih.gov/pubmed/26120493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2014.15
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