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The Critical Role of the Epidermal Growth Factor Receptor in Endochondral Ossification

Loss of epidermal growth factor receptor (EGFR) activity in mice alters growth plate development, impairs endochondral ossification, and retards growth. However, the detailed mechanism by which EGFR regulates endochondral bone formation is unknown. Here, we show that administration of an EGFR-specif...

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Detalhes bibliográficos
Main Authors: Zhang, Xianrong, Siclari, Valerie A., Lan, Shenghui, Zhu, Ji, Koyama, Eiki, Dupuis, Holly L., Enomoto-Iwamoto, Motomi, Beier, Frank, Qin, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200483/
https://ncbi.nlm.nih.gov/pubmed/21887704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.502
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