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The Critical Role of the Epidermal Growth Factor Receptor in Endochondral Ossification

Loss of epidermal growth factor receptor (EGFR) activity in mice alters growth plate development, impairs endochondral ossification, and retards growth. However, the detailed mechanism by which EGFR regulates endochondral bone formation is unknown. Here, we show that administration of an EGFR-specif...

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Bibliografski detalji
Glavni autori: Zhang, Xianrong, Siclari, Valerie A., Lan, Shenghui, Zhu, Ji, Koyama, Eiki, Dupuis, Holly L., Enomoto-Iwamoto, Motomi, Beier, Frank, Qin, Ling
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200483/
https://ncbi.nlm.nih.gov/pubmed/21887704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.502
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