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Epidermal Growth Factor Receptor (EGFR) Signaling Promotes Proliferation and Survival in Osteoprogenitors by Increasing Early Growth Response 2 (EGR2) Expression

Maintaining bone architecture requires continuous generation of osteoblasts from osteoprogenitor pools. Our previous study of mice with epidermal growth factor receptor (EGFR) specifically inactivated in osteoblast lineage cells revealed that EGFR stimulates bone formation by expanding the populatio...

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Autors principals: Chandra, Abhishek, Lan, Shenghui, Zhu, Ji, Siclari, Valerie A., Qin, Ling
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711314/
https://ncbi.nlm.nih.gov/pubmed/23720781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.447250
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