Recurrent Tissue-Specific mtDNA Mutations Are Common in Humans

Mitochondrial DNA (mtDNA) variation can affect phenotypic variation; therefore, knowing its distribution within and among individuals is of importance to understanding many human diseases. Intra-individual mtDNA variation (heteroplasmy) has been generally assumed to be random. We used massively para...

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Hlavní autoři: Samuels, David C., Li, Chun, Li, Bingshan, Song, Zhuo, Torstenson, Eric, Boyd Clay, Hayley, Rokas, Antonis, Thornton-Wells, Tricia A., Moore, Jason H., Hughes, Tia M., Hoffman, Robert D., Haines, Jonathan L., Murdock, Deborah G., Mortlock, Douglas P., Williams, Scott M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820769/
https://ncbi.nlm.nih.gov/pubmed/24244193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003929
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