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Macrophage and T Cell Produced IL-10 Promotes Viral Chronicity
Chronic viral infections lead to CD8(+) T cell exhaustion, characterized by impaired cytokine secretion. Presence of the immune-regulatory cytokine IL-10 promotes chronicity of Lymphocytic Choriomeningitis Virus (LCMV) Clone 13 infection, while absence of IL-10/IL-10R signaling early during infectio...
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| Hoofdauteurs: | , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820745/ https://ncbi.nlm.nih.gov/pubmed/24244162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003735 |
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