Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria

Macrophages (Mϕ) play a central role as effector cells in immunity to intracellular pathogens such as Mycobacterium. Paradoxically, they also provide a habitat for intracellular bacterial survival. This paradoxical role of Mϕ remains poorly understood. Here we report that this dual role may emanate...

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Detalhes bibliográficos
Main Authors: Verreck, Frank A. W., de Boer, Tjitske, Langenberg, Dennis M. L., Hoeve, Marieke A., Kramer, Matthijs, Vaisberg, Elena, Kastelein, Robert, Kolk, Arend, de Waal-Malefyt, René, Ottenhoff, Tom H. M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384786/
https://ncbi.nlm.nih.gov/pubmed/15070757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400983101
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