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WSX-1 Signalling Inhibits CD4(+) T Cell Migration to the Liver during Malaria Infection by Repressing Chemokine-Independent Pathways
IL-27 is an important and non-redundant regulator of effector T cell accumulation in non-lymphoid tissues during infection. Using malaria as a model systemic pro-inflammatory infection, we demonstrate that the aberrant accumulation of CD4(+) T cells in the liver of infected IL27R(−/−) (WSX-1(−/−)) m...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820588/ https://ncbi.nlm.nih.gov/pubmed/24244314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078486 |
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