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IL-27 Receptor Signaling Regulates Memory CD4(+) T Cell Populations and Suppresses Rapid Inflammatory Responses during Secondary Malaria Infection

Interleukin-27 (IL-27) is known to control primary CD4(+) T cell responses during a variety of different infections, but its role in regulating memory CD4(+) T responses has not been investigated in any model. In this study, we have examined the functional importance of IL-27 receptor (IL-27R) signa...

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Detalhes bibliográficos
Main Authors: Gwyer Findlay, Emily, Villegas-Mendez, Ana, O'Regan, Noelle, de Souza, J. Brian, Grady, Lisa-Marie, Saris, Christiaan J., Riley, Eleanor M., Couper, Kevin N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911875/
https://ncbi.nlm.nih.gov/pubmed/24101691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01091-13
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