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IFN-γ producing CD4(+) T cells promote experimental cerebral malaria by modulating CD8(+) T cell accumulation within the brain

It is well established that IFN-γ is required for the development of experimental cerebral malaria (ECM) during Plasmodium berghei ANKA infection of C57BL/6 mice. To date, however, the temporal and tissue-specific cellular sources of IFN-γ during P. berghei ANKA infection have not been investigated...

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Detalhes bibliográficos
Main Authors: Villegas-Mendez, Ana, Greig, Rachel, Shaw, Tovah N., de Souza, J. Brian, Findlay, Emily Gwyer, Stumhofer, Jason S., Hafalla, Julius C. R., Blount, Daniel G., Hunter, Christopher A., Riley, Eleanor M., Couper, Kevin N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393641/
https://ncbi.nlm.nih.gov/pubmed/22723523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200688
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