AICAR-dependent AMPK Activation Improves Scar Formation in the Aged Heart in a Murine Model of Reperfused Myocardial Infarction

We have demonstrated that scar formation after myocardial infarction (MI) is associated with an endogenous pool of CD44(pos)CD45(neg) multipotential mesenchymal stem cells (MSC). MSC differentiate into fibroblasts secreting collagen that forms a scar and mature into myofibroblasts that express alpha...

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Detaylı Bibliyografya
Asıl Yazarlar: Cieslik, Katarzyna A., Taffet, George E., Crawford, Jeffrey R., Trial, JoAnn, Osuna, Patricia Mejia, Entman, Mark L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820161/
https://ncbi.nlm.nih.gov/pubmed/23871790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.07.005
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