Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations

The study of the genetic and selective landscape of immunity genes across primates can provide insight into the existing differences in susceptibility to infection observed between human and non-human primates. Here, we explored how selection has driven the evolution of a key family of innate immuni...

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Autori principali: Quach, Hélène, Wilson, Daniel, Laval, Guillaume, Patin, Etienne, Manry, Jeremy, Guibert, Jessica, Barreiro, Luis B., Nerrienet, Eric, Verschoor, Ernst, Gessain, Antoine, Przeworski, Molly, Quintana-Murci, Lluis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820138/
https://ncbi.nlm.nih.gov/pubmed/23851028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt335
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