Evolutionary Dynamics of Human Toll-Like Receptors and Their Different Contributions to Host Defense

Infectious diseases have been paramount among the threats to health and survival throughout human evolutionary history. Natural selection is therefore expected to act strongly on host defense genes, particularly on innate immunity genes whose products mediate the direct interaction between the host...

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Main Authors: Barreiro, Luis B., Ben-Ali, Meriem, Quach, Hélène, Laval, Guillaume, Patin, Etienne, Pickrell, Joseph K., Bouchier, Christiane, Tichit, Magali, Neyrolles, Olivier, Gicquel, Brigitte, Kidd, Judith R., Kidd, Kenneth K., Alcaïs, Alexandre, Ragimbeau, Josiane, Pellegrini, Sandra, Abel, Laurent, Casanova, Jean-Laurent, Quintana-Murci, Lluís
格式: Artigo
語言:Inglês
出版: Public Library of Science 2009
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702086/
https://ncbi.nlm.nih.gov/pubmed/19609346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000562
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