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Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations

The study of the genetic and selective landscape of immunity genes across primates can provide insight into the existing differences in susceptibility to infection observed between human and non-human primates. Here, we explored how selection has driven the evolution of a key family of innate immuni...

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Detalhes bibliográficos
Main Authors: Quach, Hélène, Wilson, Daniel, Laval, Guillaume, Patin, Etienne, Manry, Jeremy, Guibert, Jessica, Barreiro, Luis B., Nerrienet, Eric, Verschoor, Ernst, Gessain, Antoine, Przeworski, Molly, Quintana-Murci, Lluis
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820138/
https://ncbi.nlm.nih.gov/pubmed/23851028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt335
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