Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations

The study of the genetic and selective landscape of immunity genes across primates can provide insight into the existing differences in susceptibility to infection observed between human and non-human primates. Here, we explored how selection has driven the evolution of a key family of innate immuni...

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Hoofdauteurs: Quach, Hélène, Wilson, Daniel, Laval, Guillaume, Patin, Etienne, Manry, Jeremy, Guibert, Jessica, Barreiro, Luis B., Nerrienet, Eric, Verschoor, Ernst, Gessain, Antoine, Przeworski, Molly, Quintana-Murci, Lluis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820138/
https://ncbi.nlm.nih.gov/pubmed/23851028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt335
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