Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene.

The VHL tumor suppressor gene is inactivated in patients with von Hippel-Lindau disease and in most sporadic clear cell renal carcinomas. Although VHL protein function remains unclear, VHL does interact with the elongin BC subunits in vivo and regulates RNA polymerase II elongation activity in vitro...

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Autors principals: Gnarra, J R, Zhou, S, Merrill, M J, Wagner, J R, Krumm, A, Papavassiliou, E, Oldfield, E H, Klausner, R D, Linehan, W M
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC38197/
https://ncbi.nlm.nih.gov/pubmed/8855222
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