Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene.

The VHL tumor suppressor gene is inactivated in patients with von Hippel-Lindau disease and in most sporadic clear cell renal carcinomas. Although VHL protein function remains unclear, VHL does interact with the elongin BC subunits in vivo and regulates RNA polymerase II elongation activity in vitro...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Gnarra, J R, Zhou, S, Merrill, M J, Wagner, J R, Krumm, A, Papavassiliou, E, Oldfield, E H, Klausner, R D, Linehan, W M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38197/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855222/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.10589
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Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene.

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