Similar molecules spatially correlate with lipofuscin and N-retinylidene-N-retinylethanolamine in the mouse but not in the human retinal pigment epithelium

The accumulation of lipofuscin in the retinal pigment epithelium (RPE) has been implicated in the development of age-related macular degeneration (AMD) in humans. The exact composition of lipofuscin is not known but its best characterized component is N-retinylidene-N-retinylethanolamine (A2E), a by...

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Main Authors: Ablonczy, Zsolt, Higbee, Daniel, Grey, Angus C., Koutalos, Yiannis, Schey, Kevin L., Crouch, Rosalie K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818512/
https://ncbi.nlm.nih.gov/pubmed/23969078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2013.08.005
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