Lipofuscin and N-Retinylidene-N-Retinylethanolamine (A2E) Accumulate in Retinal Pigment Epithelium in Absence of Light Exposure: THEIR ORIGIN IS 11-cis-RETINAL

The age-dependent accumulation of lipofuscin in the retinal pigment epithelium (RPE) has been associated with the development of retinal diseases, particularly age-related macular degeneration and Stargardt disease. A major component of lipofuscin is the bis-retinoid N-retinylidene-N-retinylethanola...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Boyer, Nicholas P., Higbee, Daniel, Currin, Mark B., Blakeley, Lorie R., Chen, Chunhe, Ablonczy, Zsolt, Crouch, Rosalie K., Koutalos, Yiannis
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2012
Предметы:
Cell Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381188/
https://ncbi.nlm.nih.gov/pubmed/22570475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.329235
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы