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Identification of Fragments Targeting an Alternative Pocket on HIV-1 gp41 by NMR Screening and Similarity Searching
[Image: see text] The HIV-1 envelope glycoprotein gp41 fusion intermediate is a promising drug target for inhibiting viral entry. However, drug development has been impeded by challenges inherent in mediating the underlying protein-protein interaction. Here we report on the identification of fragmen...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3817815/ https://ncbi.nlm.nih.gov/pubmed/23932360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.07.026 |
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