Metformin, at Concentrations Corresponding to the Treatment of Diabetes, Potentiates the Cytotoxic Effects of Carboplatin in Cultures of Ovarian Cancer Cells

The use of the type 2 diabetics drug metformin has been correlated with enhanced progression-free survival in ovarian cancer. The literature has speculated that this enhancement is due to the high concentration of metformin directly causing cancer cell death. However, this explanation does not fit w...

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Autores principales: Erices, Rafaela, Bravo, Maria Loreto, Gonzalez, Pamela, Oliva, Bárbara, Racordon, Dusan, Garrido, Marcelo, Ibañez, Carolina, Kato, Sumie, Brañes, Jorge, Pizarro, Javier, Barriga, Maria Isabel, Barra, Alejandro, Bravo, Erasmo, Alonso, Catalina, Bustamente, Eva, Cuello, Mauricio A., Owen, Gareth I.
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2013
Materias:
Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817664/
https://ncbi.nlm.nih.gov/pubmed/23653391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719113488441
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