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Metformin partially reverses the carboplatin-resistance in NSCLC by inhibiting glucose metabolism

Platinum-based chemotherapeutic drugs are irreplaceable for the treatment of advanced non-small cell lung cancer (NSCLC). However, acquired drug resistance has become a major obstacle for the clinical application of chemotherapy on NSCLC. In the present study, we established carboplatin-resistant NS...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Yong, He, Chunxi, Huang, Xianping
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650413/
https://ncbi.nlm.nih.gov/pubmed/29088858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20663
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