Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: an explanation for poor outcomes in obese women

The evidence linking obesity with ovarian cancer remains controversial. Leptin is expressed at higher levels in obese women and stimulates cell migration in other epithelial cancers. Here, we explored the clinical impact of overweight/obesity on patient prognosis and leptin's effects on the met...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Kato, Sumie, Abarzua-Catalan, Lorena, Trigo, César, Delpiano, Ana, Sanhueza, Cristobal, García, Karen, Ibañez, Carolina, Hormazábal, Katherine, Diaz, Daniela, Brañes, Jorge, Castellón, Enrique, Bravo, Erasmo, Owen, Gareth, Cuello, Mauricio
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2015
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673253/
https://ncbi.nlm.nih.gov/pubmed/26053184
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