Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: an explanation for poor outcomes in obese women

The evidence linking obesity with ovarian cancer remains controversial. Leptin is expressed at higher levels in obese women and stimulates cell migration in other epithelial cancers. Here, we explored the clinical impact of overweight/obesity on patient prognosis and leptin's effects on the met...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kato, Sumie, Abarzua-Catalan, Lorena, Trigo, César, Delpiano, Ana, Sanhueza, Cristobal, García, Karen, Ibañez, Carolina, Hormazábal, Katherine, Diaz, Daniela, Brañes, Jorge, Castellón, Enrique, Bravo, Erasmo, Owen, Gareth, Cuello, Mauricio
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673253/
https://ncbi.nlm.nih.gov/pubmed/26053184
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