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The oestrogen metabolite 2-methoxyoestradiol alone or in combination with tumour necrosis factor-related apoptosis-inducing ligand mediates apoptosis in cancerous but not healthy cells of the human endometrium

Cancers of the reproductive tract account for 12% of all malignancies in women. As previous studies have shown that oestrogen metabolites can cause apoptosis, we characterised the effect of oestrogen and oestrogen metabolites on non-cancerous and cancerous human endometrial cells. Herein, we demonst...

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Detalhes bibliográficos
Publicado no:Endocr Relat Cancer
Main Authors: Kato, Sumie, Sadarangani, Anil, Lange, Soledad, Villalón, Manuel, Brañes, Jorge, Brosens, Jan J, Owen, Gareth I, Cuello, Mauricio
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6112420/
https://ncbi.nlm.nih.gov/pubmed/17639050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/ERC-07-0008
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