Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression

Clinical studies have suggested a survival benefit in ovarian cancer patients with type 2 diabetes mellitus taking metformin, however the mechanism by which diabetic concentrations of metformin could deliver this effect is still poorly understood. Platelets not only represent an important reservoir...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Erices, Rafaela, Cubillos, Sofía, Aravena, Raúl, Santoro, Felice, Marquez, Monica, Orellana, Renan, Ramírez, Carolina, González, Pamela, Fuenzalida, Patricia, Bravo, María Loreto, Oliva, Bárbara, Kato, Sumie, Ibañez, Carolina, Brañes, Jorge, Bravo, Erasmo, Alonso, Catalina, García, Karen, Arab, Clemente, Torres, Vicente A., Godoy, Alejandro S., Pereira, Jaime, Bustos, Galdo, Cardenas, Julio Cesar, Cuello, Mauricio A., Owen, Gareth I.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400552/
https://ncbi.nlm.nih.gov/pubmed/28209916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15348
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