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A concise enantioselective synthesis of the guaiane sesquiterpene (−)-oxyphyllol

(−)-Oxyphyllol was prepared in only 4 steps from an epoxy enone that already served as an intermediate for the total synthesis of the anticancer guaiane (−)-englerin A. A regio- and diastereoselective Co(II)-catalyzed hydration of the olefin and a transannular epoxide opening were used as the key re...

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Autors principals: Zahel, Martin, Metz, Peter
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817518/
https://ncbi.nlm.nih.gov/pubmed/24204414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.239
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