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Transcriptional Reprogramming of CD11b(+)Esam(hi) Dendritic Cell Identity and Function by Loss of Runx3

Classical dendritic cells (cDC) are specialized antigen-presenting cells mediating immunity and tolerance. cDC cell-lineage decisions are largely controlled by transcriptional factor regulatory cascades. Using an in vivo cell-specific targeting of Runx3 at various stages of DC lineage development we...

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Hlavní autoři: Dicken, Joseph, Mildner, Alexander, Leshkowitz, Dena, Touw, Ivo P., Hantisteanu, Shay, Jung, Steffen, Groner, Yoram
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817345/
https://ncbi.nlm.nih.gov/pubmed/24204843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077490
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