Keap1-Knockdown Decreases Fasting-Induced Fatty Liver via Altered Lipid Metabolism and Decreased Fatty Acid Mobilization from Adipose Tissue

AIMS: The purpose of this study was to determine whether Nrf2 activation, via Keap1-knockdown (Keap1-KD), regulates lipid metabolism and mobilization induced by food deprivation (e.g. fasting). METHODS AND RESULTS: Male C57BL/6 (WT) and Keap1-KD mice were either fed ad libitum or food deprived for 2...

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Bibliographic Details
Main Authors: Xu, Jialin, Donepudi, Ajay C., Moscovitz, Jamie E., Slitt, Angela L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817107/
https://ncbi.nlm.nih.gov/pubmed/24224011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079841
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