Keap1 Knockdown increases markers of metabolic syndrome after long-term high fat diet feeding

The Nuclear factor-E2 related factor 2 (Nrf2)-Kelch-like ECH-associated protein 1 (Keap1) pathway upregulates antioxidant and biotransformation enzyme expression to counter cellular oxidative stress. The contribution of Nrf2 to other cellular functions, such as lipid homeostasis is emerging. The pre...

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Hauptverfasser: More, Vijay R, Xu, Jialin, Shimpi, Prajakta C, Belgrave, Clyde, Luyendyk, James P., Yamamoto, Masayuki, Slitt, Angela L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797262/
https://ncbi.nlm.nih.gov/pubmed/23507082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.03.007
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