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Genome mapping on nanochannel arrays for structural variation analysis and sequence assembly
We describe genome mapping on nanochannel arrays. In this approach, specific sequence motifs in single DNA molecules are fluorescently labeled, and the DNA molecules are uniformly stretched in thousands of silicon channels on a nanofluidic device. Fluorescence imaging allows the construction of maps...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3817024/ https://ncbi.nlm.nih.gov/pubmed/22797562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2303 |
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