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Genome mapping on nanochannel arrays for structural variation analysis and sequence assembly

We describe genome mapping on nanochannel arrays. In this approach, specific sequence motifs in single DNA molecules are fluorescently labeled, and the DNA molecules are uniformly stretched in thousands of silicon channels on a nanofluidic device. Fluorescence imaging allows the construction of maps...

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Podrobná bibliografie
Hlavní autoři: Lam, Ernest T, Hastie, Alex, Lin, Chin, Ehrlich, Dean, Das, Somes K, Austin, Michael D, Deshpande, Paru, Cao, Han, Nagarajan, Niranjan, Xiao, Ming, Kwok, Pui-Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817024/
https://ncbi.nlm.nih.gov/pubmed/22797562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2303
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