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Epigenetic Optical Mapping of 5-Hydroxymethylcytosine in Nanochannel Arrays

[Image: see text] The epigenetic mark 5-hydroxymethylcytosine (5-hmC) is a distinct product of active DNA demethylation that is linked to gene regulation, development, and disease. In particular, 5-hmC levels dramatically decline in many cancers, potentially serving as an epigenetic biomarker. The n...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Gabrieli, Tslil, Sharim, Hila, Nifker, Gil, Jeffet, Jonathan, Shahal, Tamar, Arielly, Rani, Levi-Sakin, Michal, Hoch, Lily, Arbib, Nissim, Michaeli, Yael, Ebenstein, Yuval
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6114841/
https://ncbi.nlm.nih.gov/pubmed/29924591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.8b03023
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