Single-molecule quantification of 5-hydroxymethylcytosine for diagnosis of blood and colon cancers

BACKGROUND: The DNA modification 5-hydroxymethylcytosine (5hmC) is now referred to as the sixth base of DNA with evidence of tissue-specific patterns and correlation with gene regulation and expression. This epigenetic mark was recently reported as a potential biomarker for multiple types of cancer,...

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Publicat a:Clin Epigenetics
Autors principals: Gilat, Noa, Tabachnik, Tzlil, Shwartz, Amit, Shahal, Tamar, Torchinsky, Dmitry, Michaeli, Yael, Nifker, Gil, Zirkin, Shahar, Ebenstein, Yuval
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Methodology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512773/
https://ncbi.nlm.nih.gov/pubmed/28725280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0368-9
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