Biodistribution of newly synthesized PHEA-based polymer-coated SPION in Sprague Dawley rats as magnetic resonance contrast agent

OBJECTIVES: The purpose of this study was to observe the pharmacokinetic behavior of newly synthesized biocompatible polymers based on polyhydroxyethylaspartamide (PHEA) to be used to coat an iron oxide core to make superparamagnetic iron oxide nanoparticles (SPION). MATERIALS AND METHODS: The isoto...

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Bibliografische gegevens
Hoofdauteurs: Park, Junsung, Cho, Wonkyung, Park, Hee Jun, Cha, Kwang-Ho, Ha, Dae-Chul, Choi, Youn-Woong, Lee, Ha-Young, Cho, Sun-Hang, Hwang, Sung-Joo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2013
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817023/
https://ncbi.nlm.nih.gov/pubmed/24204138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S51684
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