Biodistribution of newly synthesized PHEA-based polymer-coated SPION in Sprague Dawley rats as magnetic resonance contrast agent

OBJECTIVES: The purpose of this study was to observe the pharmacokinetic behavior of newly synthesized biocompatible polymers based on polyhydroxyethylaspartamide (PHEA) to be used to coat an iron oxide core to make superparamagnetic iron oxide nanoparticles (SPION). MATERIALS AND METHODS: The isoto...

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Main Authors: Park, Junsung, Cho, Wonkyung, Park, Hee Jun, Cha, Kwang-Ho, Ha, Dae-Chul, Choi, Youn-Woong, Lee, Ha-Young, Cho, Sun-Hang, Hwang, Sung-Joo
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2013
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817023/
https://ncbi.nlm.nih.gov/pubmed/24204138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S51684
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