Biodistribution of newly synthesized PHEA-based polymer-coated SPION in Sprague Dawley rats as magnetic resonance contrast agent

OBJECTIVES: The purpose of this study was to observe the pharmacokinetic behavior of newly synthesized biocompatible polymers based on polyhydroxyethylaspartamide (PHEA) to be used to coat an iron oxide core to make superparamagnetic iron oxide nanoparticles (SPION). MATERIALS AND METHODS: The isoto...

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Hlavní autoři: Park, Junsung, Cho, Wonkyung, Park, Hee Jun, Cha, Kwang-Ho, Ha, Dae-Chul, Choi, Youn-Woong, Lee, Ha-Young, Cho, Sun-Hang, Hwang, Sung-Joo
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2013
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817023/
https://ncbi.nlm.nih.gov/pubmed/24204138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S51684
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