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Cortical metabolism in pyruvate dehydrogenase deficiency revealed by ex vivo multiplet (13)C-NMR of the adult mouse brain
The pyruvate dehydrogenase complex (PDC), required for complete glucose oxidation, is essential for brain development. Although PDC deficiency is associated with a severe clinical syndrome, little is known about its effects on either substrate oxidation or synthesis of key metabolites such as glutam...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816779/ https://ncbi.nlm.nih.gov/pubmed/22884585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2012.07.020 |
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