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Binding of pyruvate dehydrogenase to the core of the human pyruvate dehydrogenase complex

In human (h) pyruvate dehydrogenase complex (PDC) the pyruvate dehydrogenase (E1) is bound to the E1-binding domain of dihydrolipoamide acetyltransferase (E2). The C-terminal surface of the E1β subunit was scanned for the negatively charged residues involved in binding with E2. βD289 of hE1 interact...

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Main Authors: Korotchkina, Lioubov G., Patel, Mulchand S.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262399/
https://ncbi.nlm.nih.gov/pubmed/18206651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.12.041
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