Heptanoate as a neural fuel: energetic and neurotransmitter precursors in normal and glucose transporter I-deficient (G1D) brain

It has been postulated that triheptanoin can ameliorate seizures by supplying the tricarboxylic acid cycle with both acetyl-CoA for energy production and propionyl-CoA to replenish cycle intermediates. These potential effects may also be important in other disorders associated with impaired glucose...

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Bibliografiske detaljer
Main Authors: Marin-Valencia, Isaac, Good, Levi B, Ma, Qian, Malloy, Craig R, Pascual, Juan M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564188/
https://ncbi.nlm.nih.gov/pubmed/23072752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.151
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