Pepsin promotes proliferation of laryngeal and pharyngeal epithelial cells

OBJECTIVE/HYPOTHESIS: Laryngopharyngeal reflux (LPR) is thought to be a significant risk factor for laryngeal squamous cell carcinoma (SCC), but causality has never been proven. It is accepted that chronic reflux into the esophagus can induce metaplastic changes in esophageal mucosa with subsequent...

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Bibliografiske detaljer
Main Authors: Johnston, Nikki, Yan, Justin C., Hoekzema, Craig R., Samuels, Tina L., Stoner, Gary D., Blumin, Joel H., Bock, Jonathan M.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816638/
https://ncbi.nlm.nih.gov/pubmed/22570308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.23307
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