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Pepsin promotes proliferation of laryngeal and pharyngeal epithelial cells

OBJECTIVE/HYPOTHESIS: Laryngopharyngeal reflux (LPR) is thought to be a significant risk factor for laryngeal squamous cell carcinoma (SCC), but causality has never been proven. It is accepted that chronic reflux into the esophagus can induce metaplastic changes in esophageal mucosa with subsequent...

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Autori principali: Johnston, Nikki, Yan, Justin C., Hoekzema, Craig R., Samuels, Tina L., Stoner, Gary D., Blumin, Joel H., Bock, Jonathan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816638/
https://ncbi.nlm.nih.gov/pubmed/22570308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.23307
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