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Chronic pepsin exposure promotes anchorage-independent growth, and migration of a hypopharyngeal squamous cell line

OUTCOME OBJECTIVES: 1.Investigate the role of reflux, specifically pepsin, in laryngopharyngeal carcinogenesis. 2.Evaluate effects of chronic pepsin exposure on cell migration, apoptosis, and colony forming ability in hypopharyngeal cells. STUDY DESIGN: Translation research. SETTING: Academic resear...

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Pubblicato in:Otolaryngol Head Neck Surg
Autori principali: Kelly, Elizabeth A., Samuels, Tina L., Johnston, Nikki
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423599/
https://ncbi.nlm.nih.gov/pubmed/24376122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0194599813517862
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