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Local synthesis of pepsin in Barrett’s esophagus and the role of pepsin in esophageal adenocarcinoma
OBJECTIVE: Despite widespread use of proton pump inhibitors (PPIs), the incidence of esophageal adenocarcinoma (EAC) continues to rise. PPIs reduce reflux acidity, but only transiently inactivate gastric enzymes. Nonacid reflux, specifically nonacid pepsin, contributes to carcinogenesis in the laryn...
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| 出版年: | Ann Otol Rhinol Laryngol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4750403/ https://ncbi.nlm.nih.gov/pubmed/26077392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0003489415590657 |
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